In Blow Fly, Kay Scarpetta stands at the threshold of a new life after her work as Virginia's Chief Medical Examiner has come to a jarring end.

At the close of The Last Precinct, she knew she would have to leave Richmond if she were to find any peace. She feared that she was about to be fired by the governor. More alarming, she was hounded in the media and in the courtroom, for what some claimed was her involvement in the murder of a deputy police chief.

So Scarpetta packed up her belongings and set out for the warmth and solace of the Florida sun. She is settling into a new life as a private forensic consultant and is deep into a case that has left colleagues in Louisiana profoundly disturbed. A woman is found dead in a seedy hotel, dressed to go out, keys in her hand. Her history of blackouts, and her violent outbursts while under their spell, offer more questions than clues about the cause of her death.

Then Scarpetta receives news that chills her to the core: Jean-Baptiste Chandonne - the vicious and unrepentant Wolfman, who pursued her to her very doorstep - asks to see her. From his cell on death row, he demands an audience with the legendary Dr. Scarpetta. Only to her will he tell the secrets he knows the authorities desire: the evidence that will bring a global investigation to a swift conclusion. Scarpetta, her niece Lucy, and her colleague Detective Pete Marino are left to wonder: After all the death and destruction, what sort of endgame could this violent psychopath have in mind? And could this request be somehow related to the Louisiana case?

Her friends and family by her side, Scarpetta must unravel a twisting conspiracy with an international reach and confront the shock of her life - a blow that will force her to question the loyalty and trust of all she holds dear.