Attorney Dana Hill is used to managing a stressful life: she's one of the most successful lawyers at Strong & Thurmond, mother to a young daughter, wife to a busy, self-involved man. But when she is diagnosed with breast cancer, and her twin brother turns up beaten to death in an apparent robbery-gone-wrong in the same week, the careful balance of Dana's life is sent into flux. Agreeing with the police that this is more than just a simple botched burglary, she begins to sift through the pieces of her brother's life, a life she thought she knew as well as her own, to find out who would want him dead and why.

But bad things happen in threes, her mother has told her. When Dana discovers her husband cheating, she throws herself headlong into the investigation. Delaying cancer treatment, she teams with an intuitive detective to find the link between a one-of-a-kind earring found in her brother's bedroom and a mysterious girlfriend no one seems to be able to identify. But those connected to the murder are beginning to turn up dead, the evidence trail is growing cold and someone is masquerading as a police officer, cleaning up the details as they go along.